4.4 Article

Regioselective Palladium-Catalyzed Cross-Coupling Reactions of 2,4,7-Trichloroquinazoline

Journal

SYNLETT
Volume -, Issue 4, Pages 644-648

Publisher

GEORG THIEME VERLAG KG
DOI: 10.1055/s-0029-1219391

Keywords

palladium catalysis; cross-coupling; heterocycles; regioselectivity; quinazoline

Funding

  1. NIH [P41GM081275]

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The regioselective palladium-catalyzed cross-coupling reactions of 2,4,7-trichloroquinazoline with various aryl- and heteroarylboronic acids are reported. An efficient, sequential strategy was developed that provides access to novel, functionalized heterocycles.

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