Journal
SYNLETT
Volume -, Issue 11, Pages 1753-1756Publisher
GEORG THIEME VERLAG KG
DOI: 10.1055/s-0029-1217381
Keywords
copper fluorapatite catalyst; ortho-haloanilides; intramolecular cyclization; heterogeneous catalyst
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An efficient method for the synthesis of benzoxazoles via intramolecular cyclization of ortho-haloanilides using heterogeneous copper fluorapatite catalyst is described. A variety of ortho-haloanilides (iodo-, bromo- and chloroanilides) were cyclized to the corresponding benzoxazoles, demonstrating the versatility of the reaction.
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