Journal
SYNLETT
Volume -, Issue 9, Pages 1449-1452Publisher
GEORG THIEME VERLAG KG
DOI: 10.1055/s-0029-1216743
Keywords
Mannich-type reaction; N,O-acetal; amino acid; hafnium triflate
Categories
Funding
- MEXT
- Japan Private School Promotion Foundation
Ask authors/readers for more resources
The authors demonstrated the Hf(OTf)(4)-catalyzed Mannich-type reaction of an enol silyl ether and a ketene silyl acetal with an NO-acetal leading to the preparation of amino acid derivatives. In particular, use of the N,O-acetal having a bis(trimethylsilyl)amino group directly produced N-unprotected aspartic acid derivatives after a standard aqueous workup.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available