4.4 Article

Asymmetric Synthesis of Substituted α-Amino Phosphonates with Chiral Crown Ethers as Catalysts

Journal

SYNLETT
Volume -, Issue 9, Pages 1429-1432

Publisher

GEORG THIEME VERLAG KG
DOI: 10.1055/s-0029-1217166

Keywords

Michael additions; asymmetric catalysis; chiral phase-transfer catalysis; chiral crown compounds; aminophosphonates

Funding

  1. Hungarian Scientific Research Fund [K60284, K75098]

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A simple, phase-transfer catalytic synthesis of enantioenriched phosphonoglutaminic acid derivatives (ee Lip to 86%) has been developed by using 'sugar-based' crown ether catalysts.

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