Journal
SYNLETT
Volume -, Issue 19, Pages 3123-3126Publisher
GEORG THIEME VERLAG KG
DOI: 10.1055/s-0029-1218342
Keywords
aziridines; imines; nitrogen heterocycles; organocatalysis; stereoselective reaction; ylides
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Funding
- CSIR, New Delhi
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Tertiary amine catalyzed reaction of imines with phenacyl bromide derivatives expeditiously affords functionalized aziridines in high yields and stereoselectivities in a one-pot process. Advantageously, the protocol precludes the preparation and isolation of ylides and their precursors in a separate step as they are formed ill situ.
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