Journal
SYNLETT
Volume -, Issue 17, Pages 2659-2662Publisher
GEORG THIEME VERLAG KG
DOI: 10.1055/s-0028-1083510
Keywords
electrophilic amination; asymmetric catalysis; bifunctional organocatalyst; alpha-cyanoketones
Categories
Funding
- Ministry of Education, Science, Technology (MEST)
- Korea Industrial Technology Foundation (KOTEF)
Ask authors/readers for more resources
The catalytic enantioselective electrophilic alpha-amination promoted by chiral bifunctional organocatalysts is described. Treatment of alpha-cyanoketones with azodicarboxylates as electrophilic amination reagents under mild reaction conditions afforded the corresponding alpha-aminated alpha-cyanoketones with excellent enantiomeric excesses (87-99%).
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available