Journal
SYNLETT
Volume -, Issue 7, Pages 1027-1030Publisher
GEORG THIEME VERLAG KG
DOI: 10.1055/s-2008-1072649
Keywords
Ferrier glycosylation reaction; 3,4-unsaturated sialic acid; Bi(OTf)(3)-montmorillonite K-10; 4,5-oxazoline derivative of sialic acid; sialidase inhibitor
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The reaction of the 4,5-oxazoline derivative of sialic acid with various alcohols was effectively promoted by a catalytic amount of montmorillonite K-10 clay supported Bi(OTf)(3) to produce a variety of 3,4-unsaturated sialic acids via the Ferrier glycosylation reaction in moderate yields.
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