4.4 Article

Highly efficient domino reaction for the synthesis of the erythrina and B-homoerythrina alkaloid skeleton

Journal

SYNLETT
Volume -, Issue 4, Pages 525-528

Publisher

GEORG THIEME VERLAG KG
DOI: 10.1055/s-2008-1032091

Keywords

domino reactions; erythrina alkaloids; spiro compounds; Lewis acids; indolizidine; lactams

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A Lewis acid catalyzed domino-amidation-spirocyclization reaction is described which provides the spirocyclic core of the erythrina and B-homoerythrina alkaloids, forming three bonds in one process.

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