4.4 Article

An Efficient Synthesis of Quinoxalines under Catalyst-Free and Microwave-Irradiation Conditions

Journal

SYNLETT
Volume -, Issue 20, Pages 3163-3166

Publisher

GEORG THIEME VERLAG KG
DOI: 10.1055/s-0028-1087280

Keywords

quinoxaline; heterocycles; green chemistry; 3-(omega-bromoacetyl)coumarin; microwave irradiation

Funding

  1. National Natural Science Foundation of China [20671038]
  2. Jiangsu Key Laboratory for Chemistry of Low-Dimensional Materials [JSKC07041]

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A series of quinoxaline derivatives was synthesized by the reaction of 3-(omega-bromoacetyl)coumarins with substituted 1,2-diaminobenzenes in the absence of a catalyst under microwave conditions. Reasonable yields of the products, environmentally benign and convenient workup are the advantages of this method.

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