A Mild and Efficient Catalytic Strecker Reaction of N-Alkoxycarbonylamino Sulfones with Trimethylsilyl Cyanide Using Indium(III) Chloride: A Facile Synthesis of α-Aminonitriles

The Strecker reaction of N-alkoxycarbonylamino sulfones with trimethylsilyl cyanide in the presence of catalytic amount of indium(III) Chloride at room temperature produces the corresponding protected alpha-aminonitriles in high yields.