Practical and convenient Suzuki-Miyaura coupling reaction and α-arylation using diphenylcyclopropylphosphine ligands

A new ligand, diphenylmethylcyclopropylphosphine, has successfully been applied in the palladium-catalyzed Suzuki-Miyaura coupling and alpha-arylation of ketones with aryl chlorides in moderate to high yields. An asymmetric coupling between anisyl chloride and 2-methylindan-1-one was also tested as the first trial, giving 80% yield and 41% ee with 1 mol% of Pd.