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Glaucoma and Systemic Diseases

Journal

SURVEY OF OPHTHALMOLOGY
Volume 55, Issue 1, Pages 64-77

Publisher

ELSEVIER SCIENCE INC
DOI: 10.1016/j.survophthal.2009.03.006

Keywords

Alzheimer disease; anticoagulants; antihypertensive drugs; cardiac glycosides; cardiovascular system; depression; diabetes; drug interactions; glaucoma; glaucomamedications; Helicobacter pylori; histamine H-2 receptor antagonists; hypercholesterolemia; hypertension; hypoglycemic agents; hypothyroidism; immunology; statins; steroids; thyroid supplements; topiramate

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Glaucoma management may be extremely challenging, especially in elderly patients who have a variety of systemic diseases and take multiple medications. We obtained a comprehensive medical history in patients with primary open-angle glaucoma to determine which systemic diseases are most prevalent and which systemic medications are most commonly used. We have also reviewed the literature that addresses how these concomitant diseases and medical treatments influence the management of glaucoma. Knowledge of systemic diseases and potential drug interactions, especially between various systemic. and glaucoma medications, is important for the safe management of glaucoma patients. (Surv Ophthalmol 55:64-77, 2010. (C) 2010 Elsevier Inc. All rights reserved.)

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