Journal
SURVEY OF OPHTHALMOLOGY
Volume 54, Issue 1, Pages 33-46Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.survophthal.2008.06.002
Keywords
carbonic anhydrase inhibitor; color Doppler imaging; glaucoma; ocular blood flow; scanning laser ophthalmoscopy
Categories
Funding
- Research to Prevent Blindness, New York, NY
- Merck pharmaceuticals
Ask authors/readers for more resources
The purpose of this literature review and meta-analysis was to determine what, if any effects topical carbonic anhydrase inhibitors have on ocular hemodynamics in humans. A literature review and meta-analysis was conducted to investigate the effects of topical carbonic anhydrase inhibitors oil ocular blood flow Thirty-five articles were evaluated according to the inclusion criteria with 13 manuscripts meeting requirements for statistical analysis. Each study's effect size, defined as the change in blood flow measures after treatment with topical carbonic anhydrase inhibitors, was estimated using the weighted mean difference. Based on this meta-analysis, we conclude that topical carbonic anhydrase inhibitors increase ocular blood flow velocities in the retinal circulation, central retinal and short posterior ciliary arteries, but not in the ophthalmic artery. (Surv Ophthalmol 54:3346, 2009. (C) 2009 Elsevier Inc. All rights reserved)
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available