Journal
SURGICAL ONCOLOGY-OXFORD
Volume 18, Issue 3, Pages 219-232Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.suronc.2009.02.002
Keywords
HIFU; High intensity focused ultrasound; Transrectal; Prostate cancer; Sonablate; Ablatherm; Cryotherapy; Cryosurgery; Photodynamic therapy (PDT); Focal; Hemiablation
Funding
- Medical Research Council [G0701302] Funding Source: researchfish
- MRC [G0701302] Funding Source: UKRI
- Medical Research Council [G0701302, G1002509] Funding Source: Medline
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The use of minimally-invasive ablative therapies in localised prostate cancer offer potential for a middle ground between active surveillance and radical therapy. This article reviews the evidence for cryotherapy, high intensity focused ultrasound (HIFU) and photodynamic therapy in the treatment of localised prostate cancer. These ablative technologies can deliver a minimally invasive, day case treatment with effective early cancer control and tow genitourinary morbidity. In addition, all have the ability to deliver focal therapy of only the malignant lesions within the prostate. (C) 2009 Elsevier Ltd. All rights reserved.
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