Journal
EXPERT REVIEW OF PHARMACOECONOMICS & OUTCOMES RESEARCH
Volume 15, Issue 3, Pages 487-497Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1586/14737167.2015.1024661
Keywords
cardiovascular conditions; complications; healthcare costs; mortality; prevalence; quality of life; Type 2 diabetes mellitus
Funding
- Bristol-Myers Squibb
- AstraZeneca
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Macrovascular and microvascular complications that accompany Type 2 diabetes mellitus (T2DM) add to the burden among patients. The purpose of this systematic review is to conduct a comprehensive search of the medical literature investigating the prevalence of cardiovascular (CV) complications and assess their impact on healthcare costs, quality of life and mortality among patients with T2DM in the context of microvascular complications. A total of 76 studies and reports were used in this systematic review. Hypertension was the most prevalent complication among patients with T2DM. The additional cost burden due to CV complications was higher than any other complication except end-stage renal disease. Quality of life was much lower among patients with CV complications and T2DM, and mortality was higher than either illness alone.
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