Journal
STEREOTACTIC AND FUNCTIONAL NEUROSURGERY
Volume 88, Issue 3, Pages 129-137Publisher
KARGER
DOI: 10.1159/000303524
Keywords
Deep brain stimulation; Dystonodyskinetic syndromes; Globus pallidus internus; Stereotactic model; Electrode design
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Funding
- Wyeth Foundation
- IBM Montpellier, Products and Solutions Support Center (PSSC)
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In nearly all deep brain stimulation (DBS) applications, the same quadripolar electrode design is used for different anatomical targets even if shape and volume differences exist between nuclei. Taking into account the electrode location within the internal globus pallidus (GPi) and the size of the GPi, 2 electrodes were designed in order to improve the therapeutic benefit, to minimize side effects from DBS and to obtain a more homogeneous electric field distribution. The electrodes were evaluated numerically by using a stereotactic model measuring the correlation between the electric field and the GPi. The model was applied to 26 dystonodyskinetic patients who underwent surgery for a bilateral lead implantation into the posteroventral part of the GPi. The designed electrodes produced a more homogeneous distribution of the electric field than the quadripolar electrode. Copyright (C) 2010 S. Karger AG, Basel
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