Journal
STEREOTACTIC AND FUNCTIONAL NEUROSURGERY
Volume 88, Issue 3, Pages 177-182Publisher
KARGER
DOI: 10.1159/000313870
Keywords
Capsulotomy, ventral; Obsessive-compulsive disorder; Radiosurgery
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This case regards a 34-year-old woman with severe and refractory obsessive-compulsive disorder, who was enrolled in a double-blind, randomized controlled trial of radiosurgery. She was at first submitted to a sham radiosurgical procedure, and 1 year later to an active intervention. Opposite clinical responses were observed in the follow-up of these different phases. During the sham surgery follow-up, no improvements were observed, but a remarkable amelioration was seen a few months after the active procedure. Detailed descriptions of psychopathological changes and neuroimaging findings as well as a discussion regarding the surgical technique are provided. Copyright (C) 2010 S. Karger AG, Basel
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