4.5 Article

A K-nearest neighbors survival probability prediction method

Journal

STATISTICS IN MEDICINE
Volume 32, Issue 12, Pages 2062-2069

Publisher

WILEY
DOI: 10.1002/sim.5673

Keywords

nonparametric survival analysis; survivor function; right-censored data; KaplanMeier; K-nearest neighbors; Mahalanobis distance; Cox regression; organ transplantation

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We introduce a nonparametric survival prediction method for right-censored data. The method generates a survival curve prediction by constructing a (weighted) KaplanMeier estimator using the outcomes of the K most similar training observations. Each observation has an associated set of covariates, and a metric on the covariate space is used to measure similarity between observations. We apply our method to a kidney transplantation data set to generate patient-specific distributions of graft survival and to a simulated data set in which the proportional hazards assumption is explicitly violated. We compare the performance of our method with the standard Cox model and the random survival forests method. Copyright (c) 2012 John Wiley & Sons, Ltd.

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