Journal
STATISTICAL METHODS IN MEDICAL RESEARCH
Volume 24, Issue 6, Pages 615-634Publisher
SAGE PUBLICATIONS LTD
DOI: 10.1177/0962280211419832
Keywords
Bayesian decision theory; health economic evaluation; sensitivity analysis
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Funding
- Leverhulme Foundation
- Economic and Social Research Council
- Department of Health's NIHR Biomedical Research Centres funding scheme
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Health economic evaluations have recently become an important part of the clinical and medical research process and have built upon more advanced statistical decision-theoretic foundations. In some contexts, it is officially required that uncertainty about both parameters and observable variables be properly taken into account, increasingly often by means of Bayesian methods. Among these, probabilistic sensitivity analysis has assumed a predominant role. The objective of this article is to review the problem of health economic assessment from the standpoint of Bayesian statistical decision theory with particular attention to the philosophy underlying the procedures for sensitivity analysis.
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