Microwave-assisted synthesis, characterization and biological activities of organotin (IV) complexes with some thio Schiff bases

Microwave-assisted synthesis and characterization of the organotin (IV) complexes are reported. Trigonal bipyramidal and octahedral complexes of tin (IV) have been synthesized by the reaction of dimethyltin (IV) dichloride with 4-nitrobenzanilide-S-benzyldithiocarbazate ((LH)-H-1), 4-chlorobenzanilide-S-benzyldithiocarbazate ((LH)-H-2), 4-nitrobenzanilidebenzothiazoline ((LH)-H-3) and 4-chlorobenzanilidebenzothiazoline ((LH)-H-4). The complexes so formed were characterized by elemental analysis, conductance measurements, molecular weight determinations and spectral data viz. IR, UV-Visible, H-1 and C-13 NMR. The anti-microbial activities of the ligands and their corresponding organotin (IV) complexes have been screened against various strains of bacteria and fungi. Antifertility activity against male albino rats has also been reported. (c) 2008 Elsevier B.V. All rights reserved.