Journal
SOUTHERN MEDICAL JOURNAL
Volume 101, Issue 3, Pages 292-296Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/SMJ.0b013e318164e289
Keywords
brain abscess; Cladophialophora bantiana; dematiaceous fungus; liver transplant; lung transplant
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Cladophialophora bantiana, a dematiaceous fungus, is an uncommon pathogenic organism originally thought to more commonly affect immunocompetent patients. Increasing numbers of reports, however, describe the organism affecting immunocompromised patients. Like all dematiaceous fungi, Cladophialophora can be recognized in histopathologic sections by the golden-brown coloration in the walls of the hyphae. Of all the dematiaceous fungi, Cladophialophora bantiana demonstrates the most neurotropism, which is responsible for increasing recognition of this fungus as the causative agent in brain abscesses in transplant patients. We describe one patient with a liver transplant and another with a double lung transplant, both of whom developed cerebral abscesses caused by this organism, and review the reported literature.
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