Journal
SOLID STATE SCIENCES
Volume 12, Issue 11, Pages 1861-1865Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.solidstatesciences.2010.01.021
Keywords
Glass; Adhesion peptides; Covalent immobilization; XPS
Funding
- MIUR
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Covalent attachment of adhesive peptides to biomaterials surfaces can result in the formation of a bioactive and biomimetic surface We have demonstrated that titanium surfaces grafted with adhesion peptides reproducing sequences of fibronectin and vitronectin can increase osteoblast adhesion compared to non-treated surfaces We now extend our investigation to peptide immobilization on glass for studying human osteoblast adhesion and spreading Silanization was used to anchor adhesion peptides to the glass surface through a selective or a non-selective immobilization Investigated samples were analysed by XPS spectroscopy Comparison between the results obtained using two different peptides and applying selective and non-selective immobilization will be discussed (C) 2010 Elsevier Masson SAS All rights reserved
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