Journal
ANNALS OF LABORATORY MEDICINE
Volume 35, Issue 4, Pages 454-457Publisher
KOREAN SOC LABORATORY MEDICINE
DOI: 10.3343/alm.2015.35.4.454
Keywords
Staphylococcus aureus; Methicillin resistance; Blood culture; Accuracy; Immunochromatographic test
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Funding
- Hospices Civils de Lyon
- Institut de Veil le Sanitaire (InVS)
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Staphylococcus aureus bacteremia is associated with high mortality and morbidity, requiring prompt and appropriate antimicrobial treatment. Therefore, it is important to detect methicillin-resistant S. aureus (MRSA) rapidly from blood cultures. Two immunochromatographic tests, BinaxNow S. aureus and BinaxNow PBP2a, were directly applied to 79 Bact/Alert bottles that were positive for Gram positive cocci in cluster aggregations. Sensitivity and specificity for the identification of S. aureus and determination of methicillin resistance were 94% and 87%, and 100% and 100%, respectively, with less than 30 min of performance time. These tests are efficient and rapid; these tests are valuable alternatives to more sophisticated and expensive methods used in the diagnosis of MRSA bacteremia.
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