Journal
SOFT MATTER
Volume 9, Issue 29, Pages 6752-6756Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c3sm00131h
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Funding
- British Heart Foundation [NH/11/7/29032]
- School of Chemical Engineering & Analytical Science (University of Manchester)
- Department of Chemistry (University of Surrey)
- British Heart Foundation [NH/11/7/29032] Funding Source: researchfish
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The site-specific conjugation of DNA-binding protein (Tus) to self-assembling peptide FEFEFKFKK was demonstrated. Rheology studies and TEM of the corresponding hydrogels (including PNIPAAm-containing systems) showed no significant variation in properties and hydrogel morphology compared to FEFEFKFKK. Critically, we demonstrate that Tus is accessible within the gel network displaying DNA-binding properties.
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