Journal
SOFT MATTER
Volume 8, Issue 28, Pages 7402-7407Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c2sm25725d
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Funding
- NIH [R01CA142746]
- HFSP [RGP0056/2008]
- Brandeis University
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Here we report the generation of a novel class of supramolecular hydrogelators based on the integration of nucleobases, Arg-Gly-Asp (RGD) peptides, and glucosamine in a single molecule. These novel small molecule hydrogelators self-assemble in water to form stable supramolecular nanofibers/hydrogels and exhibit useful biostability. This approach provides a new opportunity for systematic exploration of the self-assembly of small biomolecules by varying any individual segment to generate a large array of supramolecular hydrogels for biological functions and for biomedical applications.
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