4.6 Article

Molecular design of hyaluronic acid hydrogel networks for long-term controlled delivery of human growth hormone

Journal

SOFT MATTER
Volume 7, Issue 3, Pages 868-870

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c0sm01011a

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Funding

  1. Ministry of Health & Welfare, Republic of Korea [A080711]
  2. MEST [2009-0084578]
  3. Korea Health Promotion Institute [A080711] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
  4. National Research Foundation of Korea [2009-0084578] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)

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A new molecular design of hyaluronic acid (HA) hydrogel networks by Michael addition between aminoethyl methacrylated HA (HA-AEMA) and thiolated HA (HA-SH) enabled the controlled release of human growth hormone (hGH) for up to 4 weeks.

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