Journal
SOFT MATTER
Volume 7, Issue 1, Pages 147-152Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c0sm00555j
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- Hong Kong University of Science and Technology (HKUST) [RPC06/07.SC10]
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Molecular dynamics simulations were conducted to investigate phase behaviors of lamellar lipid membranes in water under a uniform external electric field. Poration, deformation and fusion of membranes were induced and water/membrane interfaces changed from perpendicular to parallel to the electric field. The hydration level of the lipids determined whether the final phase was the lamellar or inverted columnar structure. The simulations provide insights into phase transitions of amphiphile solutions in electric fields and mechanisms of cell electrofusion.
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