Journal
SOFT MATTER
Volume 7, Issue 22, Pages 10931-10934Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c1sm06303k
Keywords
-
Categories
Funding
- PRESTO-JST
- Ministry of Education, Culture, Sports, Science, and Technology, Japan [20241029]
- Grants-in-Aid for Scientific Research [20241029, 23350079] Funding Source: KAKEN
Ask authors/readers for more resources
Developing methods for stabilizing DNA nanostructures is a major challenge for next-generation nanofabrication, because stable DNA nanostructures are expected to work as building materials in the bottom-up assembly of functional biomolecules and nano-electronic components. Here we show the availability of cross-linking-type photoreaction with 3-cyanovinylcarbazole nucleosides ((CNV)Ks) on DNA nanostructures. DNA double-crossover AB-staggered (DXAB) tiles including cross-linking molecules, CNVKs, self-assembled into two-dimensional (2D) periodic DNA arrays and were covalently connected by photo-cross-linking. The self-assembled DNA arrays before and after photo-cross-linking have been visualized by high-resolution, tapping mode atomic force microscopy (AFM) in buffer. The improvement of the heat tolerance of photo-cross-linked DNA arrays was confirmed by heating and visualizing the DNA nanostructures. The heat-resistant DNA arrays may expand the potential of DNA as a functional material in biotechnology and nanotechnology.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available