Journal
ACS MACRO LETTERS
Volume 4, Issue 4, Pages 381-386Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acsmacrolett.5b00111
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Funding
- Australian Research Council (ARC) Centre of Excellence in Convergent Bio-Nano Science and Technology [CE140100036]
- Australian Laureate Fellowship from the ARC
- Faculty of Pharmacy and Pharmaceutical Sciences, Monash University
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We report on the preparation of positively charged crew-cut nanoaggregates in water with various nonspherical (i.e., worm, flower, and large compound) and spherical (i.e., vesicle and sphere) morphologies by the self-assembly of a single diblock copolymer in water. Our facile procedure for preparing positively charged nanoparticles, when combined with the techniques for obtaining negatively charged and neutral nanoaggregates already established by Eisenberg et al., provides a versatile toolbox for the reproducible production of uniformly nanostructured particles with control over both morphology and surface chemistry. Such nanoparticles offer opportunities for the fundamental study of nanobio interactions and may open the door to novel drug and gene delivery applications.
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