Journal
SOFT MATTER
Volume 5, Issue 7, Pages 1320-1327Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/b812388h
Keywords
-
Ask authors/readers for more resources
Despite impressive advances in chemistry and biology, the mimicking of the complexity and functionality of natural cells in artificial systems still remains in its infancy. Liposomes for instance have been extensively used to reproduce some basic properties of cells and particularly biological membranes, whereas other studies have focused on the elaboration of fibrous networks to represent intra- and extra cellular matrices. But so far, there are only a few examples in which both cytoskeleton and membranes have been combined. Here we discuss the different strategies towards cell construction mimics explored so far, which consist of the incorporation of artificial fibrillar networks within liposomes. These fibrillar networks can be based on polymers or self-assembled structures, and the examples illustrate how their confinement within artificial cells can affect their shape, stability or compartmentalization. The challenge for the next decades will be to develop systems capable of more complex functions like endo- and exocytosis and motility by including some of the dynamic properties of the natural cytoskeleton.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available