Journal
SOFT MATTER
Volume 4, Issue 4, Pages 647-652Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/b713013a
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Funding
- BBSRC [BB/C00759X/2] Funding Source: UKRI
- EPSRC [EP/E030173/1] Funding Source: UKRI
- Biotechnology and Biological Sciences Research Council [BB/C00759X/2] Funding Source: researchfish
- Engineering and Physical Sciences Research Council [EP/E030173/1] Funding Source: researchfish
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Programmed assembly and self-assembly of soft materials offers significant promise for the generation of new types of materials with useful properties. Through evolutionary processes occurring over billions of years, nature has produced numerous optimised building blocks for the controlled assembly of a wide range of complex architectures. Our challenge now is to imitate these naturally occurring processes for technological applications, either using biological molecules such as DNA and proteins, or macromolecular mimics that retain many of the important features of biological molecules while introducing new functionalities. We focus on a single example of biomolecular self-assembly-the self-assembly of polypeptides, including polypeptide mimics, into quasi-one-dimensional fibres-to provide a flavour of the utility of soft biological materials for construction purposes.
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