4.6 Article

Polymer-supported lipid shells, onions, and flowers

Journal

SOFT MATTER
Volume 4, Issue 9, Pages 1787-1791

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/b804933e

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Funding

  1. NIAID NIH HHS [R21 AI073165, R21 AI073165-02] Funding Source: Medline
  2. NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES [R21AI073165] Funding Source: NIH RePORTER

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Phospholipid-enveloped biodegradable polymer microparticles and nanoparticles synthesized by an emulsion-solvent evaporation process were characterized by confocal and cryoelectron micros-copies to show that the lipid envelope exhibits two-dimensional fluidity and can be configured into 'shell', 'onion', or 'flower' nanostructures, depending on the quantity and composition of lipids employed in the synthesis.

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