4.6 Article

Internal stress in kinetically trapped actin bundle networks

Journal

SOFT MATTER
Volume 4, Issue 12, Pages 2365-2367

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/b808582j

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Funding

  1. Deutsche Forschungsgemeinschaft [Ba2029/8-1]
  2. DFG-Cluster of Excellence Nanosystems Initiative Munich (NIM)
  3. ENB Bayern

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By confocal microscopy combined with local cutting of single bundles, we show that the actin binding protein filamin is already sufficient to generate prestress in in vitro actin networks by cross-linking and bundling actin filaments during network polymerization forming a kinetically trapped network structure.

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