Journal
SMALL
Volume 14, Issue 40, Pages -Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/smll.201801882
Keywords
mu-LED; bioimaging; lanthanide nanomaterials; microscopy; POCT
Categories
Funding
- Australian Research Council (ARC) Discovery Early Career Researcher Award Scheme [DE180100669]
- ARC Future Fellowship Scheme [FT 130100517]
- National Natural Science Foundation of China (NSFC) [61729501]
- Major International (Regional) Joint Research Project of NSFC [51720105015]
- Ministry of Science and Technology of Taiwan [MOST 104-2113-M-002-012-MY3]
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Half a century after its initial emergence, lanthanide photonics is facing a profound remodeling induced by the upsurge of nanomaterials. Lanthanide-doped nanomaterials hold promise for bioapplications and photonic devices because they ally the unmatched advantages of lanthanide photophysical properties with those arising from large surface-to-volume ratios and quantum confinement that are typical of nanoobjects. Cutting-edge technologies and devices have recently arisen from this association and are in turn promoting nanophotonic materials as essential tools for a deeper understanding of biological mechanisms and related medical diagnosis and therapy, and as crucial building blocks for next-generation photonic devices. Here, the recent progress in the development of nanomaterials, nanotechnologies, and nanodevices for clinical uses and commercial exploitation is reviewed. The candidate nanomaterials with mature synthesis protocols and compelling optical uniqueness are surveyed. The specific fields that are directly driven by lanthanide doped nanomaterials are emphasized, spanning from in vivo imaging and theranostics, micro-/nanoscopic techniques, point-of-care medical testing, forensic fingerprints detection, to micro-LED devices.
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