Adherence to CPAP therapy improves quality of life and reduces symptoms among obstructive sleep apnea syndrome patients

The aim of the study was to asses quality of life and symptoms of obstructive sleep apnea syndrome (OSAS) patients after adhering to 6 months of continuous positive airway pressure (CPAP) treatment. A group of 50 patients (41 men and 9 women) were diagnosed by polysomnography and treated with CPAP therapy for 6 months. Their symptoms and health-related quality of life were assessed by administering a validated and translated version of the sleep apnea quality of life index (SAQLI). Sleepiness was measured using the Epworth Sleepiness Scale (ESS) and through electronic monitoring of CPAP usage per night of sleep. Mean CPAP usage was 4.5 +/- 0.5 h per night. Comparisons between quality of life indexes before and after CPAP treatment showed an improvement in the total SAQLI score (3.8 +/- 0.9 vs. 5.8 +/- 0.8 after CPAP, p < 0.01), in daily functioning (4.2 +/- 1.4 vs. 6.0 +/- 0.9, p < 0.01), social interactions (4.8 +/- 1.3 vs.6.3 +/- 0.7, p < 0.01), emotional functioning (4.4 +/- 1.4 vs. 5.7 +/- 1.0, p < 0.01), symptoms (1.6 +/- 0.8 vs. 5.8 +/- 1.2, p < 0.01), and in the ESS (13.7 +/- 6.5 vs. 3.9 +/- 3.8, p < 0.01). Regarding the patients' symptoms, improvement was noticed for sleepiness while watching a spectacle (96%), reading (95%), carrying on a conversation (95%), driving (92.9%), restless sleep (87.8%), and urinating more than once per night (84.8%). Smaller improvements were observed for the reported dry mouth-throat upon awakening (36.1%),excessive fatigue (54.5%), and decreased energy (55.3%). We conclude that OSAS patients who adhere to nighttime CPAP therapy show significant improvement of their quality of life, daytime sleepiness, and other symptoms after 6 months of treatment with CPAP.