Journal
STEM CELL RESEARCH & THERAPY
Volume 6, Issue -, Pages -Publisher
BIOMED CENTRAL LTD
DOI: 10.1186/s13287-015-0127-9
Keywords
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Funding
- Canadian Institutes of Health Research (CIHR)
- Programme de bourses de Chercheur-boursier clinicien from Fonds De Recherche Sante Quebec
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To this end human MSCs were isolated from adipose tissue and the MSC:CD4(+) T-cell suppression was assessed in a co-culture system. In summary, this study demonstrates that advanced age, atherosclerosis and type 2 diabetes mellitus reduce the functional potency of MSCs. Optimizing the criteria for the selection of MSC donors could enhance the results of cell-based therapies.
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