Journal
SOCIAL SCIENCE & MEDICINE
Volume 132, Issue -, Pages 103-112Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.socscimed.2015.03.031
Keywords
Puberty; Perimenopause; Chronic disease; Women's health; Life course health; HPG axis; HPA axis
Funding
- Robert Wood Johnson Foundation Health & Society Scholars Program
- National Institute of Child Health and Human Development [T32-HD007275]
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This scoping review synthesizes existing research on two major transitions in females' lives: puberty and perimenopause. These two periods of vast physiological change demarcate the beginning and the end of the reproductive life cycle and are associated with major neuroendocrine reorganization across two key systems, the hypothalamic-pituitary-gonadal (HPG) axis the hypothalamus-pituitary-adrenal (HPA) axis. Despite growing evidence suggesting that the timing and experience of puberty and perimenopause are related to various physical and mental health outcomes (e.g., mood disorders, metabolism, cardiovascular health, autoimmune conditions, and cancer), these two processes are rarely examined together. In this paper, we bridge these disparate literatures to highlight similarities, isolate inconsistencies, and identify important areas for future research in women's health. (c) 2015 Elsevier Ltd. All rights reserved.
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