Journal
SCIENTIFIC REPORTS
Volume 5, Issue -, Pages -Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/srep12326
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Funding
- National Research Foundation of Korea (NRF) - Ministry of Education, Science and Technology [2012-0006689, 2014R1A2A2A09053061, CASE-2014M3A6A5060933, 2013R1A1A2A10061422]
- Yonsei University Future-leading Research Initiative
- National Research Foundation of Korea [2013R1A1A2A10061422, 2014R1A2A2A09053061] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
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Here, we developed a novel and facile method to control the local water adhesion force of a thin and stretchable superhydrophobic polydimethylsiloxane (PDMS) substrate with micro-pillar arrays that allows the individual manipulation of droplet motions including moving, merging and mixing. When a vacuum pressure was applied below the PDMS substrate, a local dimple structure was formed and the water adhesion force of structure was significantly changed owing to the dynamically varied pillar density. With the help of the lowered water adhesion force and the slope angle of the formed dimple structure, the motion of individual water droplets could be precisely controlled, which facilitated the creation of a droplet-based microfluidic platform capable of a programmable manipulation of droplets. We showed that the platform could be used in newer and emerging microfluidic operations such as surface-enhanced Raman spectroscopy with extremely high sensing capability (10(-15) M) and in vitro small interfering RNA transfection with enhanced transfection efficiency of similar to 80%.
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