4.7 Article

Ultrasensitive measurement of huntingtin protein in cerebrospinal fluid demonstrates increase with Huntington disease stage and decrease following brain huntingtin suppression

Related references

Note: Only part of the references are listed.
Article Biotechnology & Applied Microbiology

In Vivo Evaluation of Candidate Allele-specific Mutant Huntingtin Gene Silencing Antisense Oligonucleotides

Amber L. Southwell et al.

MOLECULAR THERAPY (2014)

Article Multidisciplinary Sciences

Quantification Assays for Total and Polyglutamine-Expanded Huntingtin Proteins

Douglas Macdonald et al.

PLOS ONE (2014)

Article Biochemistry & Molecular Biology

A fully humanized transgenic mouse model of Huntington disease

Amber L. Southwell et al.

HUMAN MOLECULAR GENETICS (2013)

Article Biochemical Research Methods

Single-step detection of mutant huntingtin in animal and human tissues: A bioassay for Huntington's disease

Andreas Weiss et al.

ANALYTICAL BIOCHEMISTRY (2009)

Article Clinical Neurology

Sustained Effects of Nonallele-Specific Huntingtin Silencing

Valerie Drouet et al.

ANNALS OF NEUROLOGY (2009)

Article Biochemistry & Molecular Biology

Mutant Huntingtin N-terminal Fragments of Specific Size Mediate Aggregation and Toxicity in Neuronal Cells

Tamara Ratovitski et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2009)

Article Biotechnology & Applied Microbiology

AAV vector-mediated RNAi of mutant huntingtin expression is neuroprotective in a novel genetic rat model of Huntington's disease

Nicholas R. Franich et al.

MOLECULAR THERAPY (2008)

Review Neurosciences

R6/2 neurons with intranuclear inclusions survive for prolonged periods in the brains of chimeric mice

Anton Reiner et al.

JOURNAL OF COMPARATIVE NEUROLOGY (2007)

Article Multidisciplinary Sciences

Therapeutic silencing of mutant huntingtin with siRNA attenuates striatal and cortical neuropathology and behavioral deficits

M. DiFiglia et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)

Article Biochemistry & Molecular Biology

rAAV-mediated shRNA ameliorated neuropathology in Huntington disease model mouse

Y Machida et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)

Article Neurosciences

Clinico-pathological rescue of a model mouse of Huntington's disease by siRNA

YL Wang et al.

NEUROSCIENCE RESEARCH (2005)

Article Multidisciplinary Sciences

RNA interference improves motor and neuropathological abnormalities in a Huntington's disease mouse model

SQ Harper et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)

Article Biochemistry & Molecular Biology

Selective striatal neuronal loss in a YAC128 mouse model of Huntington disease

EJ Slow et al.

HUMAN MOLECULAR GENETICS (2003)