Laser synthesis and tailor-design of nanosized gold onto carbon nanotubes for non-enzymatic electrochemical glucose sensor

The non-enzymatic cyclic and pulse voltammetric detection of glucose using pulsed laser deposited gold nanostructures onto carbon nanotubes electrodes is described for the first time. Several synthesis conditions have been considered in order to obtain various morphologies for the Au film. Among all the synthesized Au nanostructures, it is found that an Au film deposited under vacuum with 10,000 laser pulses displays a high electroactive surface area of 6.55 cm(2) and a roughness factor of 13.2. In addition, this electrode exhibits a low onset potential of -0.28 V vs. Ag/AgCl for glucose oxidation. A linear square-wave voltammetric response for oxidation of glucose was observed up to a glucose concentration of 50 mM with a sensitivity of 25 mu A cm(-2) mM(-1) and a detection limit of 0.1 mM. Finally, owing to its versatile capabilities such as robust control of the surface morphology, control of the stoichiometry and ultra-low loading of noble catalyst, it can be expected that the pulsed laser deposition (PLD) technique will emerge as a fabrication tool for on chip miniature-sized sensors in the near future. (C) 2013 Elsevier B. V. All rights reserved.