A simple non-enzymatic hydrogen peroxide sensor using gold nanoparticles-graphene-chitosan modified electrode

Gold nanoparticles (GNPs) were electrochemically deposited on the graphene and chitosan modified glassy carbon electrode and characterized by scanning electron microscope and cyclic voltammetry, respectively. A simple non-enzymatic H2O2 sensor was developed based on the direct electrochemistry of H2O2 in the presence of GNPs. Under the optimized conditions, the fabricated electrode displayed a linear response in the H2O2 concentration range from 5.0 mu M to 35 mM with a detection limit of 1.6 mu M estimated at a signal-to-noise ratio of 3. The proposed sensor presented some advantages including simple operation procedure, wide linear range, low detection limit, fast response time as well as good anti-interference performance, stability and reproducibility, which indicate it can act as a promising electrochemical platform for H2O2 detection. (C) 2014 Elsevier B.V. All rights reserved.