Related references
Note: Only part of the references are listed.VGX-1027 modulates genes involved in lipopolysaccharide-induced Toll-like receptor 4 activation and in a murine model of systemic lupus erythematosus
Paolo Fagone et al.
IMMUNOLOGY (2014)
Imbalance between Neutrophil Elastase and its Inhibitor α1-Antitrypsin in Obesity Alters Insulin Sensitivity, Inflammation, and Energy Expenditure
Virginie Mansuy-Aubert et al.
CELL METABOLISM (2013)
Manganese-Enhanced Magnetic Resonance Imaging Detects Declining Pancreatic β-Cell Mass in a Cyclophosphamide-Accelerated Mouse Model of Type 1 Diabetes
Patrick F. Antkowiak et al.
DIABETES (2013)
In Vivo JNK Activation in Pancreatic β-Cells Leads to Glucose Intolerance Caused by Insulin Resistance in Pancreas
Jordi Lanuza-Masdeu et al.
DIABETES (2013)
The potential role of dendritic cells in the therapy of Type 1 diabetes
Chin-Nien Lee et al.
IMMUNOTHERAPY (2013)
A new type of microglia gene targeting shows TAK1 to be pivotal in CNS autoimmune inflammation
Tobias Goldmann et al.
NATURE NEUROSCIENCE (2013)
Type 1 diabetes: translating mechanistic observations into effective clinical outcomes
Kevan C. Herold et al.
NATURE REVIEWS IMMUNOLOGY (2013)
TAK1 Inhibition Promotes Apoptosis in KRAS-Dependent Colon Cancers
Anurag Singh et al.
CELL (2012)
Targeting Regulatory T Cells in the Treatment of Type 1 Diabetes Mellitus
S. M. Cabrera et al.
CURRENT MOLECULAR MEDICINE (2012)
Prevention of Autoimmune Diabetes and Induction of β-Cell Proliferation in NOD Mice by Hyperbaric Oxygen Therapy
Gaetano Faleo et al.
DIABETES (2012)
TAK1 Negatively Regulates NF-κB and p38 MAP Kinase Activation in Gr-1+CD11b+ Neutrophils
Adebusola Alagbala Ajibade et al.
IMMUNITY (2012)
Activated Protein C Inhibits Pancreatic Islet Inflammation, Stimulates T Regulatory Cells, and Prevents Diabetes in Non-obese Diabetic (NOD) Mice
Meilang Xue et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Transforming growth factor beta-activated kinase 1 (TAK1)-dependent checkpoint in the survival of dendritic cells promotes immune homeostasis and function
Yanyan Wang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Signaling in Innate Immunity and Inflammation
Kim Newton et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2012)
Stopping Type 1 Diabetes: Attempts to Prevent or Cure Type 1 Diabetes in Man
Jay S. Skyler et al.
DIABETES (2011)
Type 1 Diabetes: Etiology, Immunology, and Therapeutic Strategies
Tom L. Van Belle et al.
PHYSIOLOGICAL REVIEWS (2011)
Role of dendritic cell maturity/costimulation for generation, homeostasis, and suppressive activity of regulatory T cells
Katrien Pletinckx et al.
FRONTIERS IN IMMUNOLOGY (2011)
In vivo RNAi-mediated silencing of TAK1 decreases inflammatory Th1 and Th17 cells through targeting of myeloid cells
Gabriel Courties et al.
BLOOD (2010)
Inhibition of the JNK/AP-1 pathway reduces neuronal death and improves behavioral outcome after neonatal hypoxic-ischemic brain injury
Cora H. Nijboer et al.
BRAIN BEHAVIOR AND IMMUNITY (2010)
Unexpected Acceleration of Type 1 Diabetes by Transgenic Expression of B7-H1 in NOD Mouse Peri-Islet Glia
Jason Yantha et al.
DIABETES (2010)
Intradermal α1-antitrypsin therapy avoids fatal anaphylaxis, prevents type 1 diabetes and reverses hyperglycaemia in the NOD mouse model of the disease
H. Ma et al.
DIABETOLOGIA (2010)
Immune cell crosstalk in type 1 diabetes
Agnes Lehuen et al.
NATURE REVIEWS IMMUNOLOGY (2010)
A critical role of TAK1 in B-cell receptor-mediated nuclear factor κB activation
James Schuman et al.
BLOOD (2009)
Retuning the immune system: the future of type 1 diabetes therapy?
Dan Jones
NATURE REVIEWS DRUG DISCOVERY (2009)
The role of inflammation in insulitis and β-cell loss in type 1 diabetes
Decio L. Eizirik et al.
NATURE REVIEWS ENDOCRINOLOGY (2009)
Induction of nuclear factor-κB and its downstream genes by TNF-α and IL-1β has a pro-apoptotic role in pancreatic beta cells
F. Ortis et al.
DIABETOLOGIA (2008)
Curative and β cell regenerative effects of α1-antitrypsin treatment in autoimmune diabetic NOD mice
Maria Koulmanda et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
New regulators of NF-κB in inflammation
Sankar Ghosh et al.
NATURE REVIEWS IMMUNOLOGY (2008)
The cross-talk between dendritic and regulatory T cells: good or evil?
Pascale Hubert et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2007)
Ubiquitin-mediated activation of TAK1 and IKK
A. Adhikari et al.
ONCOGENE (2007)
Dendritic cell-expanded, islet-specific CD4+ CD25+ CD62L+ regulatory T cells restore normoglycemia in diabetic NOD mice
Kristin V. Tarbell et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2007)
Tumor-derived CD4(+) CD25(+) regulatory T cell suppression of dendritic cell function involves TGF-beta and IL-10
Nicolas Larmonier et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2007)
Cyclophosphamide-induced type-1 diabetes in the NOD mouse is associated with a reduction of CD4+CD25+Foxp3+ regulatory T cells
Sven Brode et al.
JOURNAL OF IMMUNOLOGY (2006)
Transcriptional regulation via the NF-κB signaling module
A. Hoffmann et al.
ONCOGENE (2006)
TAK1 is indispensable for development of T cells and prevention of colitis by the generation of regulatory T cells
Shintaro Sato et al.
INTERNATIONAL IMMUNOLOGY (2006)
The kinase TAK1 integrates antigen and cytokine receptor signaling for T cell development, survival and function
Yisong Y. Wan et al.
NATURE IMMUNOLOGY (2006)
Essential role of TAK1 in thymocyte development and activation
Hong-Hsing Liu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Essential function for the kinase TAK1 in innate and adaptive immune responses
S Sato et al.
NATURE IMMUNOLOGY (2005)
Balance between NF-κB and JNK/AP-1 activity controls dendritic cell life and death
E Kriehuber et al.
BLOOD (2005)
Treatment with granulocyte colony-stimulating factor prevents diabetes in NOD mice by recruiting plasmacytoid dendritic cells and functional CD4(+)CD25(+) regulatory T-cells
H Kared et al.
DIABETES (2005)
Physiological β cell death triggers priming of self-reactive T cells by dendritic cells in a type-1 diabetes model
S Turley et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2003)
Elevated NF-kappa B activation in nonobese diabetic mouse dendritic cells results in enhanced APC function
B Poligone et al.
JOURNAL OF IMMUNOLOGY (2002)
TAK1 is a ubiquitin-dependent kinase of MKK and IKK
C Wang et al.
NATURE (2001)
Th1 to Th2 cytokine shifts in nonobese diabetic mice: Sometimes an outcome, rather than the cause, of diabetes resistance elicited by immunostimulation
DV Serreze et al.
JOURNAL OF IMMUNOLOGY (2001)