Ag nanoparticles self-supported on Ag2V4O11 nanobelts: Novel nanocomposite for direct electron transfer of hemoglobin and detection of H2O2

Nanocomposite of Ag nanoparticles self-supproted on Ag2V4O11 nanobelts, prepared by gamma-ray irradiation treatments of Ag2V4O11 nanobelts, was used to immobilize hemoglobin on glassy carbon electrode Detailed electrochemical analysis was performed and it was found that Ag/Ag2V4O11 nanocomposite significantly improved the direct electron transfer between hemoglobin and glassy carbon electrode, leading to the fabrication of a biosensor with a very sensitive detection of H2O2 The apparent surface concentration (Gamma*) of hemoglobin and the electron transfer rate constant (k(s)) were calculated to be 16 x 10(-10) mol/cm(2) and 26s(-1), respectively The linear detection range of H2O2 was 10-120 mu M, with a detection limit of 03 mu M (C) 2010 Elsevier B V. All rights reserved