Journal
SENSORS
Volume 12, Issue 7, Pages 9467-9475Publisher
MDPI
DOI: 10.3390/s120709467
Keywords
gold nanoparticles; Pb2+; 11-mercaptoundecanoic acid; microfluidic chip
Funding
- National Science Foundation of China [91127037, 91123037]
- General Administration of Quality Supervision, Inspection and Quarantine of PRC [2010QK294]
- Shanghai Municipal Bureau of Quality and Technical Supervision [2012-04, 2012-03]
- Shanghai Postdoctoral Sustentation Fund, China [11R21420800]
- National Basic Research Program of China [2012CB933301]
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A portable and power-free microfluidic device was designed for rapid and sensitive detection of lead (Pb2+). 11-mercaptoundecanoic acid (MUA)-functionalized gold nanoparticles (MUA-AuNPs) aggregated in the presence of Pb2+ for the chelation mechanism. When we performed this analysis on a polydimethylsiloxane (PDMS) microfluidic chip, the aggregations deposited onto the surface of chip and formed dark lines along the laminar flows in the zigzag microchannels. This visual result can be observed by the naked eye through a microscope or just a drop of water as a magnifier. Ten mu M Pb2+ was successfully detected.
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