Journal
SENSORS
Volume 10, Issue 5, Pages 4558-4576Publisher
MDPI
DOI: 10.3390/s100504558
Keywords
diabetes mellitus; glucose biosensor; point-of-care testing; performance; self-monitoring of blood glucose
Funding
- Korean Ministry of Education, Science and Technology
- 21C Frontier Functional Proteomics Program [FPR08A2-130]
- Ministry of Health, Welfare & Family Affairs, Republic of Korea [A070001]
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Blood glucose monitoring has been established as a valuable tool in the management of diabetes. Since maintaining normal blood glucose levels is recommended, a series of suitable glucose biosensors have been developed. During the last 50 years, glucose biosensor technology including point-of-care devices, continuous glucose monitoring systems and noninvasive glucose monitoring systems has been significantly improved. However, there continues to be several challenges related to the achievement of accurate and reliable glucose monitoring. Further technical improvements in glucose biosensors, standardization of the analytical goals for their performance, and continuously assessing and training lay users are required. This article reviews the brief history, basic principles, analytical performance, and the present status of glucose biosensors in the clinical practice.
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