Journal
SENSORS
Volume 8, Issue 9, Pages 6045-6054Publisher
MOLECULAR DIVERSITY PRESERVATION INT
DOI: 10.3390/s8096045
Keywords
review; sensors; small molecule biological toxin
Funding
- Ministry of Science and Technology of the People's Republic of China [2006BAD05A06]
- New Century Talent Program of Ministry of Education of People's Republic of China [NECT-04-0243]
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The following review of sensors and biosensors focuses on the determination of commonly studied small molecule biological toxins, including mycotoxins and small molecule neurotoxins. Because of the high toxicity of small molecule toxins, an effective analysis technique for determining their toxicity is indispensable. Sensors and biosensors have emerged as sensitive and rapid techniques for toxicity analysis in the past decade. Several different sensors for the determination of mycotoxins and other small molecule neurotoxins have been reported in the literature, and many of these sensors such as tissue biosensors, enzyme sensors, optical immunosensors, electrochemical sensors, quartz crystal sensors, and surface plasmon resonance biosensors are reviewed in this paper. Sensors are a practical and convenient monitoring tool in the area of routine analysis, and their specificity, sensitivity, reproducibility and analysis stability should all be improved in future work. In addition, accuracy field portable sensing devices and multiplexing analysis devices will be important requirement for the future.
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