Journal
SEMINARS IN IMMUNOPATHOLOGY
Volume 32, Issue 1, Pages 79-90Publisher
SPRINGER HEIDELBERG
DOI: 10.1007/s00281-009-0191-2
Keywords
Th17; Infection; Vaccine-induced immunity
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Funding
- Children's Hospital Of Pittsburgh
- Pennsylvania Department of Health Formula Funding
- National Institute of Health, USA [AI075106, A1083541]
- NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES [R21AI083541, R00AI075106] Funding Source: NIH RePORTER
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T helper type 17 (Th17) cells are a distinct lineage of T cells that produce the effector molecules IL-17, IL-17F, IL-21, and IL-22. Although the role of Th17 cells in primary immune responses against infections is well documented, there is growing evidence that the Th17 lineage maybe critical for vaccine-induced memory immune responses against infectious diseases. Here, we summarize recent progress in our understanding of the role of IL-17 in vaccine-induced immunity.
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