Journal
SEMINARS IN IMMUNOLOGY
Volume 24, Issue 1, Pages 43-49Publisher
ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD
DOI: 10.1016/j.smim.2011.11.004
Keywords
Antigen-presenting cells; Dendritic cells; Microenvironment; Microbiota
Categories
Funding
- European Commission
- Association for International Cancer Research (AICR)
- Associazione ltaliana per la Ricerca sul Cancro (AICR)
- Fondazione Cariplo
- Italian Ministry of Health (Ricerca finalizzata)
Ask authors/readers for more resources
Coordination of immune responses in the gut is a complex task. In order to fight pathogens and maintain a defined population of commensal microbes, the mucosal immune system has to coordinate information from the external (luminal) and internal (abluminal) environment and respond accordingly. Dendritic cells (DCs)are crucial cell types involved in this process as they integrate these signals and direct immunogenic or tolerogenic responses. Here, we review how various functions of DCs depend on microbial stimuli and how these stimuli influence the course of immune activation. (C) 2011 Elsevier Ltd. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available