Journal
SEMINARS IN IMMUNOLOGY
Volume 22, Issue 1, Pages 48-53Publisher
ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD
DOI: 10.1016/j.smim.2009.11.003
Keywords
Euprymna; Vibrio fischeri; Hemocytes; MAMP; PRR; Symbiosis; Complement
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Funding
- NIH [R01-AI50661, RR R01-12294]
- NSF [IOS 0841507]
- WM Keck Foundation
- The University of Connecticut Research Foundation
- Division Of Integrative Organismal Systems
- Direct For Biological Sciences [841507] Funding Source: National Science Foundation
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The squid-vibrio symbiosis is an experimental system being studied as a model of the chronic colonization of animal epithelia by bacterial partners. One principal question being asked with this model is: what is the role of the immune system in the dynamics of the onset and maintenance of the symbiotic state? This review focuses upon results of research to date, which have demonstrated that both cell-mediated and cell-free components of the innate immune system are involved in these processes. (C) 2009 Published by Elsevier Ltd.
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