Journal
SEMINARS IN CANCER BIOLOGY
Volume 18, Issue 3, Pages 150-163Publisher
ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD
DOI: 10.1016/j.semcancer.2007.12.002
Keywords
cholinergic anti-inflammatory pathway; neurobiology of cancer; neurotransmitters; innervation of the tumors; vagus nerve
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The interactions between the nervous, endocrine and immune systems are studied intensively. The communication between immune and cancer cells, and multilevel and bi-directional interactions between the nervous and immune systems constitute the basis for a hypothesis assuming that the brain might monitor and modulate the processes associated with the genesis and progression of cancer. The aim of this article is to describe the data supporting this hypothesis. (C) 2007 Elsevier Ltd. All rights reserved.
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